Role of Autophagy in Cadmium-Induced Hepatotoxicity and Liver Diseases

Figure 1

The schematic model represents the different environmental sources of Cd that impact liver toxicity. Cd accumulation increases liver toxicity and induces liver damage. Cd accumulation increases the expression of ALT, AST, GGT, MDA, and peroxidase activities, a prominent liver damage marker. On the other hand, pre- or postexposure with chelating agents, metals like Se and several phytochemicals could reverse the Cd-mediated hepatic toxicity/damage.