Research Article

Acute and Subchronic Toxicity Studies on the Aqueous Extract of the Plant Mixture (Bidens pilosa and Cymbopogon citratus Aerial Parts) in Rat Model

Table 2

Effects of the plant mixture aqueous extract on the relative weight of organs of females.

OrgansTNTSATBC 200BC 400BC 800SAT

Relative weight (%)Liver2.92 ± 0.052.92 ± 0.062.90 ± 0.062.82 ± 0.072.92 ± 0.113.04 ± 0.16
Kidneys0.59 ± 0.020.61 ± 0.040.57 ± 0.020.61 ± 0.030.64 ± 0.020.65 ± 0.04
Heart0.31 ± 0.010.30 ± 0.010.32 ± 0.010.29 ± 0.010.30 ± 0.010.31 ± 0.02
Lungs0.63 ± 0.050.58 ± 0.060.65 ± 0.030.66 ± 0.060.60 ± 0.070.67 ± 0.06
Brain0.85 ± 0.030.81 ± 0.020.85 ± 0.010.85 ± 0.020.83 ± 0.020.85 ± 0.02
Spleen0.43 ± 0.040.44 ± 0.010.41 ± 0.030.44 ± 0.030.47 ± 0.070.49 ± 0.03

Each value represents the mean ± SEM, n = 5. TN: normal rats receiving distilled water (10 mL/kg); TSAT: normal satellite observed 14 more days after stopping every treatment; BC 200, BC 400, and BC 800: animals receiving the aqueous extract of the mixture of B. pilosa and C. citratus at the respective doses of 200, 400, and 800 mg/kg; SAT: satellite extract at the dose of 800 mg/kg observed 14 days after stopping every treatment.