The Developmental Toxicity of Thymus schimperi Essential Oil in Rat Embryos and Fetuses

Table 7

External malformations of rat fetuses after administration of the essential oil of Thymus schimperi.

Group	Fetus	Observed malformations (%)
	Examined	AC	EC	SB	SC	KY	LD	MT	AEG
G-I (pair-fed control)	96	0	0	0	0	0	0	0	0
G-II (ad libitum)	98	0	0	0	0	0	0	0	0
G-III (CT 500 mg/kg)	86	0	0	0	0	0	0	0	0
G-IV (CT 1000 mg/kg)	82	0	0	0	0	0	0	0	0
G-V (CT 2000 mg/kg)	80	0	0	0	0	0	0	0	0

The percentage of malformations is represented as a percentage of the total number of malformations (chi-square). AC: anencephaly, EC: exencephaly, SB: spina bifida, KY; kyphosis, SC: scoliosis, LD: limb defect, MT: missed tail, and AEG: agenesis of external genitalia.