Prenatal Developmental Toxicity and Histopathological Changes of the Placenta Induced by Syzygium guineense Leaf Extract in Rats

Table 2

Pregnancy outcomes of rats treated with 70% ethanol leaf extract of Syzygium guineense.

Variables	Group
	250 mg/kg n = 10	500 mg/kg n = 10	1000 mg/kg n = 10	Control n = 10	Ad libitum control n = 10
Number of fetuses	93	91	88	95	115
Number of implantation sites/litter	9.8 ± 2.1	10.0 ± 2.5	10.0 ± 1.4	10.5 ± 0.5	11.7 ± 1.2
Number of resorption sites/litter	0.5 ± 0.8	0.9 ± 0.9	1.0 ± 0.9	1.0 ± 1.6	0.2 ± 0.4
Live fetuses/litter	9.3 ± 2.7	9.1 ± 3.5	8.8 ± 1.6	9.5 ± 1.9	11.5 ± 1.4
Dead fetuses/litter	0	0	0.2 ± 0.4	0	0
Number of male fetuses/dam	4.5 ± 1.6	4.3 ± 1.2	3.7 ± 1.5	5.0 ± 1.1	5.3 ± 1.2
Number of female fetuses/dam	4.8 ± 2.7	4.8 ± 2.4	5.3 ± 2.3	4.5 ± 2.4	6.2 ± 0.8

The results are expressed as mean ± SDM, One-Way ANOVA; n: number of dams.