Quercetin Zinc and Iron Metal Complexes Protect against Sodium Arsenite Intoxication in the Hepato-Renal System of Wistar Rats via the Oxidative Stress Pathway

Figure 4

(a) Quercetin and its metal complexes normalized aspartate aminotransferase levels in sodium-arsenite induced toxicity in rats. (b) Quercetin and its metal complexes decreased the elevated alanine amino transferase levels in sodium-arsenite induced toxicity in rats. (c) Quercetin and its metal complexes ameliorate the increased levels of creatinine in sodium-arsenite intoxicated rats. (d) Effect of quercetin and its metal complexes on levels of total protein in sodium arsenite-induced toxicity. Data are presented as the mean ± SD,  = values differ significantly from untreated sodium arsenite-intoxicated rats (), ^# = values differ significantly from normal control rats (), ^∧ = values did not differ significantly from untreated sodium arsenite-intoxicated rats (). Normal control, NaAr-induced toxicity = rats administered sodium arsenite and left untreated, NaAr + Quer = rats administered sodium arsenite and treated with 30 mg/kg quercetin, NaAr + Quer-Zn = rats administered sodium arsenite and treated with 30 mg/kg quercetin-zinc, and NaAr + Quer-Fe = rats administered sodium arsenite and treated with 30 mg/kg quercetin-iron.

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