Quercetin Zinc and Iron Metal Complexes Protect against Sodium Arsenite Intoxication in the Hepato-Renal System of Wistar Rats via the Oxidative Stress Pathway

Figure 6

Magnified views of kidney micromorphological section demonstrated by hematoxylin and eosin staining at high magnification (×400). The renal cortex, renal tubules, glomeruli, and mesangial cells as well as proximal and distal renal convoluted tubules are all visible across the various groups. (a) Normal control (normal rats). (b) NaAr-induced toxicity (sodium arsenate-intoxicated rat). (c) NaAr-Quer (sodium arsenate-intoxicated rat + 30 mg/kg quercetin treatment). (d) NaAr-Quer + Zn (sodium arsenate-intoxicatedrat + quercetin-Zn complex treatment). (e) NaAr-Quer + Fe (sodium arsenate-intoxicatedrat + quercetin-Fe complex treatment). Red arrow = degenerative changes characterized with congested proximal and convoluted renal tubules, infiltrated renal parenchyma by red inflammatory cells. T = renal tubules, G = glomerulus.