Subacute Toxicity Effects of the Aqueous Shoot Extract of Yushania alpina (K. Schum.) W.C.Lin in Sprague Dawley Rats: An Appraisal of Its Safety in Ethnomedicinal Usage

Table 3

Weekly body weights.

Treatment group	Body weight (g)
	Week 0	Week 1	Week 2	Week 3	Week 4
Male rats
Control	183.81 ± 8.47^ac	215.60 ± 10.90^abc	293.30 ± 13.80^aab	261.10 ± 12.50^aab	272.20 ± 11.30^aa
40 mg/Kg BW of Y. alpina	191.16 ± 9.31^ab	230.30 ± 16.90^aab	241.20 ± 17.80^aab	259.70 ± 15.50^aa	274.90 ± 14.00^aa
200 mg/Kg BW of Y. alpina	193.07 ± 5.71^ad	226.42 ± 5.49^ac	241.55 ± 4.69^abc	258.21 ± 4.87^aab	273.39 ± 3.64^aa
1000 mg/Kg BW of Y. alpina	188.32 ± 4.54^ac	224.21 ± 7.06^abc	244.68 ± 9.98^aab	261.00 ± 10.70^aab	277.73 ± 9.90^aa
Female rats
Control	177.31 ± 6.20^ac	204.90 ± 8.10^ab	229.30 ± 6.65^aab	244.11 ± 5.08^aa	255.41 ± 4.85^aa
40 mg/Kg BW of Y. alpina	182.16 ± 9.66^ab	206.10 ± 10.40^aab	228.90 ± 13.10^aab	243.70 ± 13.50^aa	253.40 ± 12.30^aa
200 mg/Kg BW of Y. alpina	175.48 ± 8.03^ab	209.86 ± 9.82^aab	225.60 ± 11.20^aa	238.20 ± 11.20^aa	250.00 ± 11.40^aa
1000 mg/Kg BW of Y. alpina	171.78 ± 3.92^ad	203.15 ± 5.75^ac	225.50 ± 5.79^abc	243.36 ± 6.71^aab	254.05 ± 6.01^aa

Values are expressed as of replicate measurements. Means with similar superscript alphabets within the same column and those with the same subscript alphabets within the same row are not significantly different (, One-Way ANOVA with Tukey’s Post hoc); control group rats received 10 ml/Kg BW of distilled water orally.