Subacute Toxicity Effects of the Aqueous Shoot Extract of Yushania alpina (K. Schum.) W.C.Lin in Sprague Dawley Rats: An Appraisal of Its Safety in Ethnomedicinal Usage

Table 4

Haematological traits.

Treatment group	Haematologic traits					PLT (10^9/L)
	WBC (10^9/L)	RBC (10^12/L)	Hb (g/dL)	MCHC (g/dL)	HCT (%)
Male rats
Control	11.34 ± 2.38^a	11.44 ± 1.92^a	10.98 ± 1.74^a	16.10 ± 0.71^a	70.30 ± 12.70^a	970.00 ± 351.00^ab
40 mg/Kg BW of Y. alpina	13.75 ± 1.01^a	12.60 ± 0.10^a	12.10 ± 0.26^a	14.92 ± 0.14^a	81.78 ± 1.85^a	843.00 ± 126.00^b
200 mg/Kg BW of Y. alpina	12.89 ± 1.40^a	11.69 ± 0.75^a	11.54 ± 0.52^a	15.78 ± 0.45^a	74.38 ± 4.49^a	1068.00 ± 102.00^ab
1000 mg/Kg BW of Y. alpina	11.24 ± 1.51^a	12.51 ± 0.75^a	11.30 ± 0.43^a	14.04 ± 0.67^a	81.68 ± 6.42^a	1623.00 ± 127.00^a
Female rats
Control	11.20 ± 2.24^a	10.80 ± 0.84^a	12.82 ± 0.99^a	19.66 ± 2.92^a	67.58 ± 4.33^a	905.00 ± 82.00^ab
40 mg/Kg BW of Y. alpina	12.63 ± 1.91^a	13.89 ± 2.78^a	11.66 ± 0.72^a	13.60 ± 1.72^a	97.20 ± 23.20^a	1279.00 ± 99.10^ab
200 mg/Kg BW of Y. alpina	13.17 ± 3.32^a	12.46 ± 1.31^a	12.60 ± 0.83^a	16.62 ± 3.23^a	81.32 ± 7.39^a	1123.00 ± 81.70^ab
1000 mg/Kg BW of Y. alpina	16.42 ± 4.31^a	10.61 ± 1.31^a	13.74 ± 1.24^a	20.28 ± 3.77^a	72.90 ± 7.25^a	790.00 ± 103.00^b

Values are presented as of replicate experiments. Means with similar superscript alphabets within the same column are not significantly different (, One-Way ANOVA with Tukey’s Post hoc); control group rats received 10 ml/Kg BW of distilled water orally. WBC: white blood cells; RBC: red blood cells; Hb: haemoglobin; MCHC: mean corpuscular haemoglobin concentration; HCT: haematocrit; PLT: platelets.