Research Article

Subacute Toxicity Effects of the Aqueous Shoot Extract of Yushania alpina (K. Schum.) W.C.Lin in Sprague Dawley Rats: An Appraisal of Its Safety in Ethnomedicinal Usage

Table 6

Selected organ weights.

Treatment groupOrgan weights
LiverSpleenKidney (L)Kidney (R)

Male rats
 Control8.53 ± 0.49a1.08 ± 0.09a0.91 ± 0.09a0.90 ± 0.08a
 40 mg/Kg BW of Y. alpina8.54 ± 0.59a0.97 ± 0.08a0.89 ± 0.06ab0.89 ± 0.07a
 200 mg/Kg BW of Y. alpina8.06 ± 0.68a1.16 ± 0.11a0.89 ± 0.05ab0.84 ± 0.04a
 1000 mg/Kg BW of Y. alpina7.99 ± 0.55a1.20 ± 0.10a0.85 ± 0.05ab0.88 ± 0.04a

Female rats
 Control8.13 ± 0.28a1.02 ± 0.08a0.88 ± 0.02ab0.88 ± 0.02a
 40 mg/Kg BW of Y. alpina7.25 ± 0.51a0.85 ± 0.11a0.74 ± 0.05ab0.74 ± 0.08a
 200 mg/Kg BW of Y. alpina6.25 ± 0.57a0.95 ± 0.06a0.67 ± 0.03b0.72 ± 0.03a
 1000 mg/Kg BW of Y. alpina7.12 ± 0.59a0.90 ± 0.04a0.73 ± 0.02ab0.68 ± 0.02a

Values are expressed as of replicate experiments. Means with similar superscript alphabets within the same column are not significantly different (, One-Way ANOVA with Tukey’s Post hoc); control group rats received distilled water (10 ml/Kg BW; p.o).