Nephroprotective Effect of Asparagus africanus Lam. Root Extract against Gentamicin-Induced Nephrotoxicity in Swiss Albino Mice

Table 3

The effects of A. africanus root extract on gentamicin-induced nephrotoxic mice.

Groups	Creatinine (mg/dl)	Uric acid (mg/dl)	BUN (mg/dl)
Group I (normal control)	0.62 ± 0.01	1.72 ± 0.04	22.71 ± 0.90
Group II (GM 100 mg/kg)	1.88 ± 0.01^a	3.84 ± 0.05^a	42.72 ± 0.69^a
Group III (GM 100 mg/kg + sylim100 mg/kg)	0.67 ± 0.02^b	1.66 ± 0.06^b	23.66 ± 0.36^b
Group IV (extract 200 mg/kg)	1.78 ± 0.01^b	3.28 ± 0.07^b	42.36 ± 0.64
Group V (extract 400 mg/kg)	0.79 ± 0.01^b	1.67 ± 0.02^b	23.08 ± 0.38^b

The results were expressed as mean ± SD. GM = gentamicin. The results were analyzed by analysis of variance (ANOVA) followed by the Tukey multiple comparison test; n = 5. a = significant difference compared to group I, b = significant difference compared to group II, and was considered statistically significant.