Acute and Subchronic Toxicity Study of Flavonoid Rich Extract of Glycyrrhiza glabra (GutGard®) in Sprague Dawley Rats

Table 1

Effect of GutGard on body weight and gross pathology during 14-day (acute) oral toxicity.

Dose (mg/kg)	Mean body weight			Change in body weight (0–7) %	Change in body weight (7–14) %	Change in body weight (0–14) %	Gross pathological changes
	Day 0	Day 7	Day 14
5000	201.73 ± 3.63	214.30 ± 3.51	226.40 ± 3.43	6.23 ± 0.22	5.65 ± 0.24	12.23 ± 0.32	Not observed

Mean ± SD (n = 3).