Research Article
Assessment of Safety Profile of Activated Curcumin C3 Complex (AC3®), Enriched Extract of Bisdemethoxycurcumin from the Rhizomes of Curcuma longa
Table 12
Effect of absolute organ weights (g) of animals in reproductive/developmental toxicity study of AC3®.
| Treatment groups | Male | Female | Testes | Epididymidis | Seminal vesicle & coagulation gland | Ovaries | Uterus with cervix |
| Vehicle control | 2.997 ± 0.309 | 1.247 ± 0.097 | 1.948 ± 0.448 | 0.098 ± 0.014 | 0.471 ± 0.220 | Low dose-125 mg/kg b.w | 2.866 ± 0.403 | 1.175 ± 0.199 | 1.817 ± 0.492 | 0.103 ± 0.014 | 0.557 ± 0.225 | Mid dose-250 mg/kg b.w | 2.878 ± 0.477 | 1.143 ± 0.183 | 1.989 ± 0.383 | 0.085 ± 0.019 | 0.436 ± 0.113 | High dose-500 mg/kg b.w | 3.012 ± 0.371 | 1.278 ± 0.252 | 1.968 ± 0.346 | 0.088 ± 0.017 | 0.499 ± 0.410 |
|
|
Values are expressed as mean ± SD for the treatment groups. n = 10 (for both male and female animals).
|