Acetylsalicylic Acid Promotes Osteogenic Differentiation of Human Dental Pulp Mesenchymal Stem Cells and Regeneration of Alveolar Bone in Experimental Periodontitis Rats

Figure 5

The expression of inflammatory cytokines in gingival tissue samples. (a) ASA-hDPMSCs treatment reduced the levels of tumor necrosis factor-α (TNF-α) control vs. periodontitis  = 0.0021; periodontitis vs. ASA  = 0.0082; periodontitis vs. ASA-DPMSCs  = 0.0030; n = 3 for all the groups and (b) interleukin-1β (IL-1β). Control vs. periodontitis  = 0.0228; periodontitis vs. ASA  = 0.0015; periodontitis vs. DPMSCs  = 0.0131; periodontitis vs. ASA-DPMSCs  = 0.0109. n = 3 for all the groups. The results were expressed as the mean ± SD.  < 0.05 versus periodontitis group;  < 0.01 versus periodontitis group. The results were expressed as the mean ± SD.

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