Mapping the Landscape of Magnetic Field Effects on Neural Regeneration and Repair: A Combined Systematic Review, Mathematical Model, and Meta-Analysis

Figure 2

Publications aimed at studying neural repair as a function of magnetic field exposure offer a wide range of diversity in both magnetic field parameters and cell types under study. Manuscripts were counted based on if the included data fell into certain categorical variable classification. In the case of where a manuscript had data falling into multiple categories, the manuscript was counted in every category. Full-text refers to all data within the “passed full-text sample” category (n = 38), while mathematical model sample refers to any manuscript where at least one datapoint was included in the mathematical model (n = 21). See Table S3 for exclusion criteria. (a) Species of cells. (b) Cell type. NSC = neural stem cells; iPSC = induced pluripotent stem cells; NPCs = neural progenitor cells; NB = neuroblastoma; SchCs = Schwann cells; Hipp N = hippocampal neurons; Astro = astrocytes; Chro cells = chromaffin cells; DRG = dorsal root ganglia; Oligo = oligodendrocytes; Cortical N = cortical neurons. (c) Type of magnetic field. (d) Magnitude of magnetic field. (e) Frequency of magnetic field. (f) Metric of repair/regeneration studied. (g) Percent of time exposed (time exposed to magnetic field over total time of experiment and outcome measurement). (h) Total time of magnetic field exposure h = hours, d = days, and w = weeks.

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