Modelling Skeletal Muscle Ageing and Repair In Vitro

Figure 4

Volcano plots capturing significantly upregulated and downregulated genes in human muscle cells during regeneration vs. baseline. Volcano plots of young (a) and aged (b) muscle cells showing the number of upregulated and downregulated gene transcripts at the end of proliferation in the regeneration period (END PROL) compared to baseline and at the end of the regenerative process in young (c) and aged (d) muscle cells vs. control. Red and green dots indicate significantly upregulated and downregulated genes between timepoints, respectively. Blue dots denote genes not differentially expressed genes in END PROL or END DIFF vs. control. n = 4.

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