Modelling Skeletal Muscle Ageing and Repair In Vitro

Figure 6

GO enrichment analysis of young and aged muscle cells show dissimilar responses. Dot plot shows overrepresented GO terms of biological processes, molecular functions, and cellular locations at the baseline (CTRL) vs. at the end of the proliferation during the regeneration period (END PROL) in young (a) and aged (b) and CTRL vs. at the end of the regeneration period (END DIFF) in young (c) and aged (d) muscle cells. The size of the dot is based on the gene count enriched in the pathway, and the color of the dot denotes pathway enrichment significance. GO enrichment bar chart of biological processes shows most enriched GO terms in young (e) and aged (f) muscle cells at the END DIFF. n = 4.

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