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Journal of Tropical Medicine
Volume 2010, Article ID 603174, 6 pages
http://dx.doi.org/10.1155/2010/603174
Research Article

Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines

1Department of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu 210029, China
2Department of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, Philippines
3Center for International Health Research, Rhode Island Hospital, Providence, RI 02906, USA
4International Health Institute, Brown University School of Medicine, Providence, RI 02912, USA
5Department of Pathology and Laboratory Medicine, Brown University Medical School, Providence, RI 02912, USA
6Department of Pediatrics, Brown University Medical School, Providence, RI 02912, USA

Received 17 August 2009; Revised 20 October 2009; Accepted 19 January 2010

Academic Editor: Luis Eduardo Cuevas

Copyright © 2010 Jin-Mei Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cysticercosis is a significant public health problem in countries where pigs are raised for consumption and remains an important cause of neurological disease worldwide. The Philippines is considered an endemic area for cysticercosis because cases in both humans and pigs have been reported; however, epidemiologic information stays limited. We conducted a pilot survey of the seroprevalence of human cysticercosis in a village in Leyte, the Philippines, by measuring antibody specific for Taenia solium cyst-fluid antigen. There were 497 subjects aged 7–30 years in our study and most subjects were infected with one or more helminths. The overall cysticercosis seroprevalence in this population was 24.6% (95% CI: 20.82% ~ 28.58%) with no significant difference based on age, sex, or other helminth coinfection status. Although the sample may not be representative of the whole community, the findings suggest that cysticercosis is a significant, but underrecognized public health concern in the Philippines.