Investigation of Association between Susceptibility to Leprosy and SNPs inside and near the BCHE Gene of Butyrylcholinesterase

Table 2

Results from a forward stepwise multiple logistic regression in which leprosy (0 = contact control, 1 = patient) was the dependent variable.

Independent  variables^a	B ± S.E.	Wald	df	𝑃	Odds ratio (95% C.I.)
Median age	0.91±0.25	13.03	1	0.000	2.48 (1.51 to 4.05)
SNP rs4387996	−0.45±0.20	5.34	1	0.021	0.64 (0.44 to 0.93)
SNP rs1799807	1.64±0.79	4.34	1	0.037	5.18 (1.10 to 24.33)
Constant	−2.19±0.97	5.07	1	0.024	0.11

^aMedian age (≤51 = 1, >51 = 2); SNP rs4387996 (𝐺𝐺=1,𝐺𝐴=2,𝐴𝐴=3); SNP rs1799807 (70𝐺𝐺=1,70𝐷𝐺=2). Other independent variables were not significant: rs2863381; rs4440084; rs1126680; rs1803274 and sex.