Safety of a New Chewable Formulation of Mebendazole for Preventive Chemotherapy Interventions to Treat Young Children in Countries with Moderate-to-High Prevalence of Soil Transmitted Helminth Infections
Table 1
Patient demographics and baseline characteristics.
2–5 years
6–10 years
Total
()
()
()
Sex, (%)
Boys
132 (49)
74 (59)
206 (52)
Girls
139 (51)
51 (41)
190 (48)
Race, (%)
White
3 (1)
1 (1)
4 (1)
Black or African
267 (99)
124 (99)
391 (99)
Not reported
1 (0.4)
0
1 (0.3)
Age (yrs)
Mean (SD)
3.5 (1.07)
7 (1.19)
4.6 (1.94)
Baseline BMI (kg/m2)
268
125
393
Mean (SD)
14.5 (1.99)
14.5 (1.97)
14.5 (1.98)
Subgroup egg counts, (%)
Not donea
31 (11)
13 (10)
44 (11)
No infectionb
124 (46)
33 (26)
157 (40)
Lightc
109 (40)
72 (58)
181 (46)
Moderated
7 (3)
7 (6)
14 (3)
A. lumbricoides egg count, (%)
No infectionb
226 (83)
102 (82)
328 (83)
Lightc
10 (4)
6 (5)
16 (4)
Moderated
4 (1)
4 (3)
8 (2)
A. lumbricoides eggs per gram of fecese
Mean (SD)
249.2 (1805.36)
399.4 (2359.70)
297.0 (1996.27)
T. trichiura egg count, (%)
No infectionb
131 (48)
40 (32)
171 (43)
Lightc
105 (39)
66 (53)
171 (43)
Moderated
4 (1)
6 (5)
10 (2)
T. trichiura eggs per gram of fecese
Mean (SD)
143.3 (355.79)
244.7 (360.54)
175.6 (359.92)
Hookworm egg count, (%)
No infectionb
212 (78)
83 (66)
295 (74)
Lightc
28 (10)
29 (23)
57 (14)
Hookworm eggs per gram of fecese
Mean (SD)
43.0 (196.65)
99.9 (264.28)
61.1 (221.63)
BMI: body mass index.
aEgg count evaluation not conducted.
bNegative finding for egg count evaluation.
cEgg count evaluation finding is (A. lumbricoides (epg)): 1–4,999; (T. trichiura (epg)): 1–999; (Hookworms (epg)): 1–1,999.
dModerate: egg count evaluation finding is (A. lumbricoides (epg)): 5,000–49,999; (T. trichiura (epg)): 1,000–9,999; (Hookworms (epg)): 2,000–3,999.
eFor eggs per gram of feces, the number of children included were 2–5 years ; 6–10 years ; total . For children infected with multiple parasites, the grouping is based on the most severe infection.
