Dengue Virus Entry as Target for Antiviral Therapy

Table 1

Susceptible cell types for DENV infection and putative DENV receptors.

Species	Cell type	Cell description	DENV receptor(s)	References
Monkey	Vero	Kidney epithelium cells	Heparan sulfate (HS)	[28, 29]
			Glycoprotein (74 kDa)	[30]
	LLC-MK2	Kidney cells	Glycosphingolipid	[31]
Human	Monocytes	Primary myeloid cells	CD14/LPS	[32]
			HSP70/HSP90	[33]
			Fc-receptor	[13, 14, 17]
	Dendritic cells	Primary myeloid cells	DC-SIGN	[34, 35]
	Macrophages	Primary myeloid cells	Mannose receptor	[36]
			CLEC5A	[37]
	Huh	Hepatocytes	HS	[38, 39]
	HepG2	Hepatocytes	Laminin receptor, GRP78, HS	[40, 41]
	HMEC-1	Dermal endothelium	β3 integrin	[42]
Hamster	BHK	Kidney fibroblast cells	HS	[43]
			Glycosphingolipid	[44]
	CHO	Ovary cells	HS	[28, 29]
Insect	C6/36	A. albopictus larvae cells	Laminin receptor (37/67 kDa)	[45]
			HSP related (45 kDa)	[46, 47]
			Prohibitin (35 kDa)	[48]
	CCL-125	A. Aegypti larvae cells	Prohibitin (35 kDa)	[48]
	AP-61	A. pseudoscutellaris larvae cells	Glycosphingolipid	[31]