On Programmed Cell Death in Plasmodium falciparum: Status Quo
DNA fragmentation as illustrated by the TUNEL assay and agarose gel electrophoresis. Plot regions are denoted as nonfragmented (NF) and fragmented (FR). (a) TUNEL results showing parasites at 5.0% parasitaemia (blue) and parasites at parasitaemia of 7.2%, which failed to progress beyond the ring stage (green), after a decline from a high parasitaemia of >11%. (b) TUNEL results of untreated parasites (blue) and parasites treated with DNase 1 (red). (c) Agarose gel electrophoresis of genomic DNA from intact untreated (left) and DNase 1-treated (right) parasites showing a smear of DNA fragments.
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