Figure 1: DNA fragmentation as illustrated by the TUNEL assay and agarose gel electrophoresis. Plot regions are denoted as nonfragmented (NF) and fragmented (FR). (a) TUNEL results showing parasites at 5.0% parasitaemia (blue) and parasites at parasitaemia of 7.2%, which failed to progress beyond the ring stage (green), after a decline from a high parasitaemia of >11%. (b) TUNEL results of untreated parasites (blue) and parasites treated with DNase 1 (red). (c) Agarose gel electrophoresis of genomic DNA from intact untreated (left) and DNase 1-treated (right) parasites showing a smear of DNA fragments.