Research Article

Reorganization of Extracellular Matrix in Placentas from Women with Asymptomatic Chagas Disease: Mechanism of Parasite Invasion or Local Placental Defense?

Figure 3

Histopathological analysis of placentas from mothers infected with T. cruzi. Chorionic villi from T. cruzi-infected placentas (b) show severe tissue damage compared to control villi from healthy noninfected woman (a). Detachment and disorganization of the syncytiotrophoblast (arrow) as well as fetal connective tissue destruction of the villous stroma (arrowhead) is observed. Chorionic villi were processed for routine histological techniques and stained with hematoxylin-eosin. Bar scale: 25 μm.
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(a)
758357.fig.003b
(b)