Comparative Evaluation of Permissiveness to Dengue Virus Serotype 2 Infection in Primary Rodent Macrophages
Figure 3
Immunocytochemistry for DENV2-infected or noninfected macrophages. (a) Noninfected macrophage control. (b) Macrophages from DENV-infected BALB/c mice at 1 MOI, 72 hours p.i. Observe the staining in almost all cells (arrows). Note the extracellular vesicles immunoreactive to viral antigen (arrow heads). (c) Hamster macrophages DENV-infected at MOI 1, 72 hours p.i. The stained cells show an intracytoplasmatic viral antigen distribution; the other animals showed a similar labelling pattern. The bars correspond to 40 μm.
