Clinical Study
Visceral Leishmaniasis with Associated Common, Uncommon, and Atypical Morphological Features on Bone Marrow Aspirate Cytology in Nonendemic Region
Table 5
Comparison of hematological and bone marrow findings of the present study with previous studies in leishmaniasis.
| | Bhatia et al. [3] (% of cases) | Daneshbod et al. [4] (% of cases) | Present study (% of cases) |
| Peripheral blood smear | | | | Pancytopenia | 75 | 10 | 96.2 | Anemia | — | 70 | 100 | Thrombocytopenia | — | 30 | 100 | Leucopenia | — | 07 | 96.2 | Monocytosis | 62 | — | 18.5 | Nucleated RBC | 69 | — | 22.2 | Bone marrow aspirate cytology | | | | Distribution of LD bodies | | | | Intrahistiocytic | 44 | — | 00 | Extrahistiocytic | 31 | — | 3.7 | Mixed | 25 | 69 | 96.2 | Plasmacytosis | 56 | 77.9 | 96.2 | Eosinophilia | — | 27.4 | 14.8 | Free cytoplasmic bodies | | | | With LD bodies | — | 31.3 | 3.7 | Without LD bodies | — | 75.4 | 14.8 | Granular bodies | — | 51.9 | 00 | Erythroid hyperplasia | 38 | 78.9 | 81.4 | Increased histiocytes | 81 | — | 100 | Hemophagocytosis | 75 | 6.8 | 70.3 | Intracellular nonhistiocytic LD bodies | 25 | 5.9 | 10.4 | Plasma cells with abnormal inclusions | 38 | 2.4 | 14.8 | Increased blasts | 06 | 01 | — | Spore like organisms | — | 11.8 | — | Aggregates of LD bodies | 56.2 | 15.7 | 11.1 | Kinetoplast only | — | 8.8 | 3.7 | Pseudo-Pelger-Huet | 25 | 4.9 | 00 | Giant cells | — | 7.8 | 3.7 | Atypical histiocytes (Tart cell, foam cells, and RS cells) | 25 | 25.4 | 00 | Bone marrow biopsy | | | | Necrosis | 12 | 2.4 | 10.4 | Granuloma | 68 | 23 | 5.2 | Increased fibrotic foci | 19 | 4.4 | 10.4 | Increased vascularity | 63 | 5.9 | 31.5 |
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