Research Article

Congenital Rubella Syndrome in Fiji, 1995–2010

Box 1

WHO diagnostic classification for CRS.
“Suspected” CRS
Includes any infant less than one year old, presenting with heart disease, suspicion of
deafness, or one or more of the following eye signs: cataract, diminished vision, nystagmus,
squint, microphthalmus, congenital glaucoma, or where the mother has a history of suspected
or confirmed rubella during pregnancy even when the infant shows no signs of CRS.
“Clinically confirmed” CRS
Includes any infant less than one year old who has at least two of the complications listed in
(a) or one in (a) and one in (b) below:
(a) Cataract, congenital glaucoma, congenital heart disease, loss of hearing, pigmentary retinopathy
(b) Purpura, splenomegaly, radiolucent bone disease, jaundice that begins within 24 hours after birth.
“Laboratory confirmed” CRS
Includes any infant less than one year old, with clinically-confirmed CRS who has a positive
blood test for rubella specific IgM or in whom rubella virus is detected in specimens from
pharynx or urine.
CRS: congenital rubella syndrome.