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Journal of Tropical Medicine
Volume 2014 (2014), Article ID 142382, 8 pages
Research Article

Clinical, Laboratory, and Management Profile in Patients of Liver Abscess from Northern India

1Department of Medicine, PGIMER, Dr. RML Hospital, New Delhi 110001, India
2Department of Microbiology, PGIMER, Dr. RML Hospital, New Delhi 110001, India

Received 18 February 2014; Revised 15 April 2014; Accepted 20 May 2014; Published 4 June 2014

Academic Editor: Luis E. Cuevas

Copyright © 2014 Soumik Ghosh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Statistical analysis: Appropriate statistical analysis was done between clinically independent variables and outcome parameters to test for significance (p<0.05). Chi square test was applied in Table A which shows that solitary right sided LA in alcoholic patients were significantly amebic in etiology; whereas left sided abscess with ascites and associated weight loss pointed more towards tubercular origin. Chi square test analysis in Table B shows that abscess involving both lobes of liver have increased incidence of pleural effusion. In Table C, non-invasive mode of drainage of LA was analyzed, which showed that large abscess causing hepatomegaly were better drained by pig tail catheterization; however percutaneous needle aspiration had a better outcome in right-sided LA. In Table D, prognosis was evaluated using chi square test which revealed incidence of death was high in female patients, patients who had fever, icterus, ascites and pleural effusion. Continuous variables like abscess volume and duration of hospitalization was evaluated with correlation and regression statistics. In Table E, Spearman’s rank correlation and multivariate regression analysis was used to assess factors contributing to the volume of abscess measured on ultrasound. TLC, SGOT, SGPT, ALP levels and INR value were found to be directly proportional to abscess volume. In Table F, duration of hospitalization in all patients of LA was similarly analyzed. ESR, blood urea, bilirubin SGOT, ALP levels and INR value were directly proportional to the total number of days of hospitalization.

  1. Supplementary Materials