Table of Contents Author Guidelines Submit a Manuscript
Journal of Tropical Medicine
Volume 2014, Article ID 872608, 8 pages
Research Article

Frequency and Clinical Manifestations of Dengue in Urban Medellin, Colombia

1Instituto Colombiano de Medicina Tropical, Universidad CES, Sabaneta, Antioquia, Colombia
2Biogen Idec, Cambridge, MA 02142, USA
3El Paso County Public Health, Colorado Springs, CO 80907, USA
4Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia
5Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA

Received 2 February 2014; Revised 26 April 2014; Accepted 26 April 2014; Published 29 May 2014

Academic Editor: Carlos E. P. Corbett

Copyright © 2014 Berta Nelly Restrepo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A dengue fever surveillance study was conducted at three medical facilities located in the low-income district of San Javier in Medellin, Colombia. During March 2008 to 2009, 781 patients with fever regardless of chief complaint were recruited for acute dengue virus infection testing. Of the 781 tested, 73 (9.3%) were positive for dengue infection. Serotypes DENV-2 (77%) and -3 (23%) were detected by PCR. One patient met the diagnostic criteria for dengue hemorrhagic fever. Only 3 out of 73 (4.1%) febrile subjects testing positive for dengue infection were diagnosed with dengue fever by the treating physician. This study confirms dengue virus as an important cause of acute febrile illness in Medellin, Colombia, but it is difficult to diagnose without dengue diagnostic testing.