Evidence of HLA-DQB1 Contribution to Susceptibility of Dengue Serotype 3 in Dengue Patients in Southern Brazil

Table 1

Comparison of the frequencies of class I HLA alleles between the control group and patients with clinical-serologic diagnoses of dengue infection in the South of Brazil, occurring in 2007 during a serotype 3 virus epidemic.

HLA	Patients (95)		Controls (173)
	𝑛	%	𝑛	%
A∗01	12	6.3	38	11.0
A∗02	44	23.2	98	28.3
A∗03	27	14.2	30	8.7
A∗11	10	5.3	16	4.6
A∗23	12	6.3	16	4.6
A∗24	17	8.9	33	9.5
A∗25	6	3.2	3	0.9
A∗26	7	3.7	12	3.5
A∗29	11	5.8	13	3.8
A∗30	8	4.2	20	5.8
A∗31	5	2.6	13	3.8
A∗32	7	3.7	8	2.3
A∗33	5	2.6	9	2.6
A∗34	0	0.0	1	0.3
A∗36	3	1.6	1	0.3
A∗66	2	1.1	1	0.3
A∗68	9	4.7	29	8.4
A∗74	5	2.6	5	1.4
B∗07	32	4.7	30	6.9
B∗08	20	2.1	14	4.6
B∗13	10	2.6	7	2.0
B∗14	16	5.3	13	4.3
B∗15	45	9.5	32	8.1
B∗18	26	5.8	20	6.9
B∗27	10	2.1	4	2.0
B∗35	63	12.1	37	14.2
B∗37	4	1.1	4	0.6
B∗38	15	3.2	15	3.8
B∗39	13	3.2	13	3.5
B∗40	14	3.2	21	6.6
B∗41	10	1.6	6	0.0
B∗42	7	1.6	3	0.6
B∗44	49	10.5	46	7.8
B∗45	7	0.5	2	1.4
B∗46	0	0.0	0	0.3
B∗48	3	1.6	2	0.0
B∗49	9	1.1	8	3.5
B∗50	10	2.6	9	2.0
B∗51	39	8.4	29	11.8
B∗52	10	3.2	2	1.2
B∗53	14	3.2	10	1.4
B∗54	0	0.0	0	0.3
B∗55	5	1.6	5	2.0
B∗56	2	1.1	2	0.3
B∗57	15	3.2	5	1.4
B∗58	13	3.7	10	2.0
B∗81	4	0.5	0	0.3
B∗82	2	1.1	1	0.0
C∗01	12	4	6	2.9
C∗02	38	21	19	6.1
C∗03	41	19	34	11.6
C∗04	86	35	55	17.1
C∗05	20	7	24	4.0
C∗06	46	18	27	7.2
C∗07^a	93	28	86	22.5
C∗08	19	10	20	4.9
C∗12	41	21	24	8.4
C∗14	9	2	10	3.5
C∗15	23	9	19	4.0
C∗16	20	8	22	6.9
C∗17	14	5	5	0.6
C∗18	6	3	1	0.3

𝑛: allelic number. ^a𝑃=0.037, OR = 0.59 (CI 95% = 0.37–0.95).