Research Article

Pattern, Clinical Characteristics, and Outcome of Meningitis among HIV-Infected Adults Admitted in a Tertiary Hospital in North Western Tanzania: A Cross-Sectional Study

Table 1

Baseline demographic and clinical characteristics of HIV-infected adults admitted with features of meningitis to the medical wards of Bugando Medical Centre between November 2012 and May 2013 ().

CharacteristicValue median (IQR) or number (%)

Age in years39 (32.5–47)

Female gender 41 (68.3%)

Marital status
 Single9 (15%)
 Married31 (51.7%)
 Separated/divorced/widowed20 (33.3%)

Urban area of residence43 (71.7%)

Occupation
 Unemployed/self-employed54 (90%)
 Employed6 (10%)

Body mass index (kg/m2)20.6 (19.1–22.4)

Symptoms and signs on admission
 Headache60 (100%)
 Duration of headache (days)8 (7–14)
 Vomiting38 (63.3%)
 Duration of vomiting (days)2.5 (2–5)
 History of weight loss34 (56.7%)
 Fever documented at the time of admission49 (81.7%)
 Altered mental status33 (55.0%)
 Neck stiffness45 (75.0%)
 Photophobia25 (41.7%)
 Kerning’s sign positive26 (43.3%)
 Brudzinski sign positive15 (25.0%)

HIV status on admission
 Known30 (50%)
 New diagnosis30 (50%)

Baseline CD4 count (cells/uL)89 (31–226)

Nadir CD4 count (cells/uL) in known HIV-infected patients55 (15–225)

Most recent CD4 count (cells/uL) in known HIV-infected patients92.5 (35.5–260.5)

Currently receiving ART18 (30%)

Duration on ART (months) 16 [3–32]

Peripheral blood WBC (×103/uL)5.6 (4.9–7.3)

Peripheral blood WBC differential
 Neutrophils (%)67.6 (52.5–73.8)
 Lymphocytes (%)23.2 (18.2–33.6)
 Monocytes (%)6.7 (4.3–8.3)

Hemoglobin level (g/dL)11.1 (7.85–12.3)

ESR (mm/1st hour)45 (35–65)