Research Article

Pattern, Clinical Characteristics, and Outcome of Meningitis among HIV-Infected Adults Admitted in a Tertiary Hospital in North Western Tanzania: A Cross-Sectional Study

Table 3

Clinical predictors of mortality among 60 HIV-infected adults patients admitted with meningitis to medical wards of Bugando Medical Centre, Mwanza.

Predictive factor (variable)⁢Meningitis patients value
Death () number (%) or median (IQR)Alive () number (%) or median (IQR)

Age in years40 [32–46]39 [33–47]0.55

Gender
 Male8 (42.1)11 (57.9)0.376
 Female14 (34.1)27 (65.9)

Marital status
 Married10 (32.3)21 (67.7)0.321
 Not married12 (41.4)17 (58.6)

Occupation
 Unemployed19 (35.2)35 (64.8)0.384
 Employed3 (50)3 (50)

Residence
 Rural4 (23.5)13 (76.5)0.151
 Urban18 (41.9)25 (58.1)

Duration of headache
 ≤14 (days)18 (37.5)30 (62.5)0.534
 >14 (days)4 (33.3)8 (66.7)

Vomiting
 Yes14 (36.8)24 (63.2)0.597
 No8 (36.4)14 (63.6)

Duration of vomiting
 ≤7 days12 (33.3)24 (66.7)0.129
 >7 days2 (100)0

Fever
 Yes17 (34.7)32 (65.3)0.367
 No5 (45.5)6 (54.5)

Altered mental status
 Yes15 (45.5)18 (54.5)0.098
 No7 (25.9)20 (74.1)

Neck stiffness
 Yes18 (40)27 (60)0.272
 No4 (26.7)11 (73.3)

Photophobia
 Yes6 (24)19 (76)0.073
 No16 (45.7)19 (54.3)

Kerning’s sign
 Yes12 (46.2)14 (53.8)0.144
 No10 (29.4)24 (70.6)

Brudzinski sign
 Yes8 (53.3)7 (46.7)0.109
 No14 (31.1)31 (68.9)

Baseline CD4 count (cells/uL)50 [15–100]98 [46–338]0.01

Recent CD4 count (cells/uL)59.5 [30–132]100 [46–338]0.08

On ART
 Yes5 (27.8)1 3 (72.2)0.263
 No17 (40.5)25 (59.5)

Duration on ART32 [10–83]14 [3–27]0.29

LP opening pressure
 <20 cm H2O11 (32.4)23 (67.6)0.300
 ≥20 cm H2O11 (42.3)15 (57.7)

CSF appearance
 Turbid20 (90.9)2 (9.1)<0.001
 Nonturbid/clear2 (5.2)36 (94.8)

India ink
 Yes3 (37.5)5 (62.5)0.623
 No19 (36.5)33 (63.5)

Etiology confirmed meningitis
 Yes7 (50)7 (50)0.192
 No15 (32.6)31 (67.4)