Review Article

Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach

Table 1

List of antimalarial agent sources and their biological compounds.

ActinobacteriaCompoundTesting approachReference

Streptomyces ochraceus and Streptomyces bottropensisTrioxacarcins (Trioxacarcin A, B C D)In vitro testing[20]
Streptomyces sp. MSU-2110CoronamycinsIn vitro testing[21]
Streptomyces NRRL 3052
Munumbicins, E-4 and E-5In vitro testing[22]
Streptomyces NRRL 30562Munumbicin DIn vitro testing[23]
Streptomyces spectabilis BCC 4785Metacycloprodigiosin
In vitro testing[24]
Streptomyces sp. NRRL 30566Kakadumycin A
In vitro testing[25]
Streptomyces sp. SUK 10Gancidin-WIn vivo testing[26]
Streptomyces albidoflavusAntimycin A18In vitro testing[27]
Streptomyces sp. CS,
bafilomycin A1In vitro testing[28]