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Journal of Tropical Medicine
Volume 2017 (2017), Article ID 9241238, 6 pages
https://doi.org/10.1155/2017/9241238
Research Article

Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania

1Kibong’oto Infectious Diseases Hospital, P.O. Box 12, Sanya Juu, Siha, Tanzania
2Kilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania
3Kilimanjaro Clinical Research Institute, P.O. Box 2236, Moshi, Tanzania

Correspondence should be addressed to Edson W. Mollel; zt.ca.irck@lellom.e

Received 5 May 2017; Revised 19 June 2017; Accepted 20 June 2017; Published 20 July 2017

Academic Editor: Shyam Sundar

Copyright © 2017 Edson W. Mollel and Jaffu O. Chilongola. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Problem. Factors related to MDRTB mortality in Tanzania have not been adequately explored and reported. Objectives. To determine demographic, clinical, radiographic, and laboratory factors associated with MDRTB mortality in a Tanzanian TB Referral Hospital. Methodology. This was a cross-sectional study with 193 participants. Demographic, clinical, laboratory, and radiological data were collected, and their associations with mortality among MDRTB patients were determined. Results and Conclusions. Cough was the commonest finding among these MDRTB patients, with 179 (92.75%) of them presenting with cough, followed by chest X-ray consolidation in 156 patients (80.83%) and history of previous TB treatment in 151 patients (78.24%). Cigarette smoking, HIV positivity, and low CD4 counts were significantly associated with MDRTB mortality, values of 0.034, 0.044, and 0.048, respectively. Fever on the other hand was at the borderline with value of 0.059. We conclude that cigarette smoking and HIV status are significant risk factors for mortality among MDRTB patients. HIV screening should continually be emphasized among patients and the general community for early ARTs initiation. Based on the results from our study, policy makers and public health personnel should consider addressing tobacco cessation as part of national TB control strategy.