Hepatitis B Virus Infection in Tanzania: Current Status and Challenges

Table 1

Interpretation of Hepatitis B results [4].

Component	Test results	Interpretation
HBsAg	Negative	Susceptible to infection
Anti-HBc	Negative
Anti-HBs	Negative
HBsAg	Negative	Immune due to previous infection
Anti-HBc	Positive
Anti-HBs	Positive
HBsAg	Negative	Immune due to Hepatitis B vaccination
Anti-HBc	Negative
Anti-HBs	Positive
HBsAg	Positive	Acute hepatitis B infection
Anti-HBc	Positive
IgM anti-HBc	Positive
Anti-HBs	Negative
HBsAg	Positive	Chronic Hepatitis B infection
IgG anti-HBc	Positive
IgM anti-HB	Negative
Anti-HBs	Negative
HBsAg	Negative	Either: (1) Resolved infection; (2) “Low level” chronic infection; (3) Resolving acute infection
Anti-HBc	Positive
Anti-HBs	Negative
HBeAg	Positive	Presence of active HBV replication and high infectivity
HBsAg	Negative	Occult HBV infection
Anti-HBc	Positive/Negative
HBV DNA	Positive