Table 1: Interpretation of Hepatitis B results [4].

ComponentTest resultsInterpretation

HBsAgNegativeSusceptible to infection
Anti-HBcNegative
Anti-HBsNegative

HBsAgNegativeImmune due to previous infection
Anti-HBcPositive
Anti-HBsPositive

HBsAgNegativeImmune due to Hepatitis B vaccination
Anti-HBcNegative
Anti-HBsPositive

HBsAgPositiveAcute hepatitis B infection
Anti-HBcPositive
IgM anti-HBcPositive
Anti-HBsNegative

HBsAgPositiveChronic Hepatitis B infection
IgG anti-HBcPositive
IgM anti-HBNegative
Anti-HBsNegative

HBsAgNegativeEither: 
(1) Resolved infection 
(2) “Low level” chronic infection 
(3) Resolving acute infection
Anti-HBcPositive
Anti-HBsNegative

HBeAgPositivePresence of active HBV replication and high infectivity

HBsAgNegativeOccult HBV infection
Anti-HBcPositive/Negative
HBV DNAPositive