Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite

Figure 6

Structure of candidate SMTs for repurposing: varespladib (top left), its orally bioavailable pro-drug, methyl-varespladib (top right), prinomastat (bottom left), and marimatsat (bottom right). Marimastat and prinomastat are both orally bioavailable and could be combined (mixed or copackaged) for more extensive coverage as field antidotes [1, 54].