Antimalarial Activity of Tinospora baenzigeri against Plasmodium berghei-Infected Mice

Figure 2

Antimalarial activity of Tinospora baenzigeri against Plasmodium berghei-infected mice. Groups of mice (5 mice of each) were inoculated with 1 × 10⁷ parasitized erythrocytes of PbANKA by IP injection. They were then administered orally by gavage with 100, 250, and 500 mg/kg of extract once a day for 4 consecutive days. Parasitemia was then determined by microscopic analysis of Giemsa-stained thin blood smear. , , and , compared to the untreated group. UN, untreated group; CQ, 10 mg/kg of chloroquine; ns, not significant. Results shown (mean ± SEM; n = 5 per group) were representative of 2 independent experiments.