Antimalarial Activity of the Leaf Latex of Aloe weloensis (Aloaceae) against Plasmodium berghei in Mice

Table 3

Effect of Aloe weloensis on the temperature, weight, and packed cell volume of Plasmodium berghei-infected mice in the 4-day suppressive test.

Group	Dose (mg/kg)	BWt D0	BWt D4	Temp D0	Temp D4	PCV D0	PCV D4
NC	10 ml	28.80 ± 0.37	27.760 ± 0.23	37.12 ± 0.16	35.64 ± 0.36	49.60 ± 1.36	40.60 ± 1.81
AW100	100	28.00 ± 0.71	30.00 ± 0.37	37.34 ± 0.16	36.10 ± 0.27	48.00 ± 0.71	45.00 ± 0.95
AW200	200	26.80 ± 0.37	30.60 ± 1.52	36.58 ± 0.13	36.36 ± 0.31	48.80 ± 0.73	46.00 ± 0.63
AW400	400	28.60 ± 0.51	31.80 ± 0.68	36.54 ± 0.18	37.02 ± 0.07	49.00 ± 0.56	47.60 ± 1.08
CQ25	25	26.60 ± 0.51	32.60 ± 0.73	36.72 ± 0.12	37.12 ± 0.10	47.20 ± 0.37	48.80 ± 0.80

Data were expressed as mean ± SEM (n = 5); D₀: before treatment; D₄: after completing treatment. Values are significantly different () as compared to negative control. Values are more significantly different () as compared to negative control. Abbreviations: AW, Aloe weloensis; BWt, body weight (g); CQ, chloroquine; NC, negative control; PCV, packed cell volume; Temp, temperature; SEM, standard error of mean.