Chemical Synthesis, Efficacy, and Safety of Antimalarial Hybrid Drug Comprising of Sarcosine and Aniline Pharmacophores as Scaffolds

Table 6

The CC₅₀ values of the different antimalarial drugs against vero cells.

SN	Drugs	Mean CC50 in μg/ml	SD
1	Sarcosine-aniline hybrid	50.18	3.53
2	Chloroquine	57.96	3.85
3	Artesunate	19.69	3.26
4	Doxorubicin	1.96	0.59
The CC50 values of sarcosine-aniline hybrid versus other antimalarial drugs
SN	Cell type to be compared	Mean difference	value
1	Vero sarcosine-aniline hybrid VS vero chloroquine	−7.78	0.006
2	Vero sarcosine-aniline hybrid VS vero artesunate	30.48
3	Vero sarcosine-aniline hybrid VS vero doxorubicin	48.21