Efficacy of Praziquantel for the Treatment of Human Schistosomiasis in Ethiopia: A Systematic Review and Meta-Analysis

Table 2

Adverse side effects observed among individuals treated with 40 mg/kg praziquantel in Ethiopia.

Adverse events reported	No. of studies	Patients treated	Treated patients showing AEs	Incidence (%)	95% CI
					Lower limit	Upper limit
Abdominal pain/cramp	7	1217	842	69.2	66.5	71.8
Diarrhea	6	1158	419	36.2	33.4	39.0
Headache	7	1217	345	28.3	25.8	30.9
Nausea	5	1066	317	29.7	27.0	32.6
Vomiting	7	1217	305	25.1	22.6	27.6
Dizziness	4	839	237	28.2	25.2	41.4
Bloody stool	5	1108	184	16.6	14.5	18.9
Body weakness	2	724	157	21.7	18.7	24.9
Fever	4	537	138	25.7	22.1	29.6
Fatigue	4	537	126	23.5	19.9	27.3
Straining	2	283	116	40.9	35.2	46.9
Itching	5	629	89	14.1	11.5	17.1
Drowsiness	3	478	88	18.4	15.0	22.2
Haematuria	1	65	65	98.5	91.7	100.0
Epigastric pain	2	694	63	9.1	7.0	11.5
Dysuria	2	283	58	20.5	15.9	25.7
Stomachache	1	59	10	16.9	8.4	28.9
Dermatological code	1	101	9	8.9	4.2	16.2
Sweating	1	59	4	6.8	1.9	16.5
Body/skin rash	1	195	3	1.5	0.3	4.4
Swelling	1	195	3	1.3	0.3	4.4
Any one of these AEs	7	1217	1079	88.7	86.7	90.4