Cytokine Response Profiles of School-Aged Children Infected with Schistosomiasis before and after Praziquantel Treatment

Table 2

Comparison of mean MFI differences of each cytokine.

Cytokines	Pretreatment	6 weeks after treatment	12 weeks after treatment	value ()
IFN-γ	3.53 (95% CI: 0.01384 to 1.605)	2.72 (95% CI: 0.01784 to 1.609)	2.72 (95% CI: −0.7918 to 0.7998)	0.023
TNF-α	6.13 (95% CI: −2.179 to 2.626)	5.90 (95% CI: −4.195 to 0.6108)	7.92 (95% CI: −4.418 to 0.3872)	0.095 NS
IL-10	6.08 (95% CI: 1.370 to 3.145)	3.82 (95% CI: 1.320 to 3.095)	3.87 (95% CI: −0.9378 to 0.8378)	0.001
IL-5	6.89 (95% CI: 1.132 to 3.756)	4.45 (95% CI: 1.263 to 3.887)	4.32 (95% CI: −1.181 to 1.443)	0.0001
IL-4	3.86 (95% CI: −1.014 to 1.699)	3.52 (95% CI: 0.08924 to 2.803)	2.41 (95% CI: −0.2532 to 2.460)	0.033
IL-2	4.08 (95% CI: 0.1094 to 1.399)	3.33 (95% CI: 0.3338 to 1.624)	3.10 (95% CI: −0.4206 to 0.8694)	0.001

 = highly significant.  = moderately significant.  = slightly significant. NS=not significant.