Research Article

Temporal Validation of a Predictive Score for Death in Children with Visceral Leishmaniasis

Table 2

Coefficients from the Sampaio et al. 2010 study obtained in the derivation cohort and recalibrated after procedure of logistical recalibration.

Coefficient derivation cohortCoefficient validation cohort recalibrated

Constant−4.497735−3.6151509
Dyspnea1.0152330.5304422
Associated infections1.0034390.5242800
Neutrophils <500/mm³1.1454030.5984538
Jaundice1.4909080.7789744
Mucosal bleeding1.4156290.7396424
Platelets <50,000/mm³2.4588881.2847277

Adjustment of the constant term: (−1.2651599) + 0.5224832 × (−4.497735) = −3.6151509. Adjustment of dyspnea coefficient: 0.52248321.015233 = 0.5304422. Adjustment of associated infections coefficient: 0.52248321.003439 = 0.5242800. Adjustment of neutrophil <500/mm³ coefficient: 0.52248321.145403 = 0.5984538. Adjustment of jaundice coefficient: 0.52248321.490908 = 0.7789744. Adjustment of mucosal bleeding coefficient: 0.52248321.415629 = 0.7396424. Adjustment of platelets <50,000/mm³coefficient: 0.52248322.458888 = 1.2847277.