In Vivo Antimalarial Activity of Leaf Latex of Aloe melanacantha against Plasmodium berghei Infected Mice

Table 2

Four-day chemosuppression antimalarial activities and effect on survival time of leaf latex of A. melanacantha against Plasmodium berghei infected mice.

Test substance	Doses (mg/kg)	% parasitemia	% suppression	Survival days
Distilled water	10 ml/kg	29.6 ± 2	0	6.00
A. melanacantha	100 mg/kg	25.2 ± 1.92^a	14.86	8.6 ± 1.67^a
Leaf latex	200 mg/kg	21 ± 1.4^a	29	9.8 ± 0.83^a
	400 mg/kg	16.8 ± 2.38^a	43.2	8.8 ± 2^a
Chloroquine	10 mg/kg	0.00^b	100	ND

Data were expressed as mean ± standard deviation (n = 5) where a = significant compared to the control group, b = significant compared to control group, and ND = no death within the follow-up period.