In Vivo Antimalarial Activity of Leaf Latex of Aloe melanacantha against Plasmodium berghei Infected Mice

Table 4

Effect of A. melanacantha leaf latex on body temperature of Plasmodium berghei infected mice.

Test substance	Doses (mg/kg)	D0	D4	% Change
Distilled water	10 ml/kg	37.51 ± 0.21	37.3 ± 0.29	−0.21
A. melanacantha	100 mg/kg	37.1 ± 0.16	36.97 ± 0.19	−0.13^a
Leaf latex	200 mg/kg	37 ± 0.5	36.94 ± 0.59	−0.06^a
	400 mg/kg	37.1 ± 0.42	37.39 ± 0.19	0.09^a
Chloroquine	10 mg/kg	36.8 ± 0.55	36.86 ± 0.69	0.01^b

Values are expressed as mean ± standard deviation (n = 5), a = significant compared to the control group, b = significant compared to the control group, D0 = day 0, and D4 = day 4.