Single Nucleotide Polymorphisms of Pfdhfr and Pfdhps Genes: Implications for Malaria Prophylactic Strategies in Maiduguri, Northeast Nigeria
Table 1
Baseline characteristics of the subjects whose samples were analyzed.
Variable
Value
Number enrolled (%)
63 (100.0)
UMTH
20 (31.7)
MSMH
24 (38.1)
TV
19 (30.2)
Age (years)
Mean ± SD
23.6 ± 8.7
Range
2.0–67.0
Number < 5 (%)
8 (7.6)
Sex
Female (%)
35 (55.6)
Male (%)
28 (44.4)
Axillary temperature (°C)
Mean ± SD
38.6 ± 3.7
Range
36.8–40.2
Weight (kg)
Mean ± SD
49.6 ± 9.4
Range
5.0–74.0
Duration of illness (days)
Mean ± SD
3.1 ± 1.6
Range
1.0–5.0
Haematocrit (%)
Mean ± SD
39.1 ± 5.3
Range
25.0–46.0
Number < 30 (%)
17 (27.0)
Symptoms (%)
Abdominal pain
27 (42.9)
Body ache
21 (33.3)
Fever
33 (52.4)
Headache
42 (66.7)
Joint pain
8 (12.7)
Nausea and vomiting
19 (30.2)
Poor appetite
29 (46.0)
Weakness
11 (17.5)
Parasite density (/μl blood)
Geometric mean
8,948
Range
2,100–13,400
SP use in the last 12 months (%)
Yes
44 (69.8)
No
19 (30.2)
MSMH: Muhammed Shuwa Memorial Hospital, SD: Standard Deviation; SP: Sulfadoxine-pyrimethamine, UMTH: University of Maiduguri Teaching Hospital, and TV: Teachers’ Village.