Research Article

Single Nucleotide Polymorphisms of Pfdhfr and Pfdhps Genes: Implications for Malaria Prophylactic Strategies in Maiduguri, Northeast Nigeria

Table 1

Baseline characteristics of the subjects whose samples were analyzed.

VariableValue

Number enrolled (%)63 (100.0)
 UMTH20 (31.7)
 MSMH24 (38.1)
 TV19 (30.2)
Age (years)
 Mean ± SD23.6 ± 8.7
 Range2.0–67.0
 Number < 5 (%)8 (7.6)
Sex
 Female (%)35 (55.6)
 Male (%)28 (44.4)
Axillary temperature (°C)
 Mean ± SD38.6 ± 3.7
 Range36.8–40.2
Weight (kg)
 Mean ± SD49.6 ± 9.4
 Range5.0–74.0
Duration of illness (days)
 Mean ± SD3.1 ± 1.6
 Range1.0–5.0
Haematocrit (%)
 Mean ± SD39.1 ± 5.3
 Range25.0–46.0
 Number < 30 (%)17 (27.0)
Symptoms (%)
 Abdominal pain27 (42.9)
 Body ache21 (33.3)
 Fever33 (52.4)
 Headache42 (66.7)
 Joint pain8 (12.7)
 Nausea and vomiting19 (30.2)
 Poor appetite29 (46.0)
 Weakness11 (17.5)
Parasite density (/μl blood)
 Geometric mean8,948
 Range2,100–13,400
SP use in the last 12 months (%)
 Yes44 (69.8)
 No19 (30.2)

MSMH: Muhammed Shuwa Memorial Hospital, SD: Standard Deviation; SP: Sulfadoxine-pyrimethamine, UMTH: University of Maiduguri Teaching Hospital, and TV: Teachers’ Village.