Research Article

Single Nucleotide Polymorphisms of Pfdhfr and Pfdhps Genes: Implications for Malaria Prophylactic Strategies in Maiduguri, Northeast Nigeria

Table 2

Single nucleotide polymorphisms of Pfdhps codons S436A, A437G, and K540E.

CodonAllelePrevalence (%)

S436AS436 (wild)45 (71.4)
436A (mutant)14 (22.2)
S436/436A (mixed)4 (6.4)

A437GA437 (wild)41 (65.1)
437G (mutant)17 (27.0)
A437/437G (mixed)5 (7.9)

K540EK540 (wild)63 (100.0)
540E (mutant)0 (0.0)
K540/540E (mixed)0 (0.0)

S436A/A437G436A/437G (mutant)3 (4.8)