Review Article

The Impact of Mass Drug Administration on Lymphatic Filariasis

Table 2

Microfilaria and antigenic cases at baseline and after MDA implementation reported by lymphatic filariasis (LF) studies.

Reference, countryDiagnostic methodBaseline LF cases (N)LF cases (N); years of MDAI
MfAntigenMfAntigen

[14], MaliThick blood film & ICT244 (1139)0 (760); 6
[15], American SamoaThick blood smear & ICT483 (3018)5 (1881); 643 (1881); 6
[16], EgyptThick blood smear, ICT & RACT115 (1000)190 (1000)2 (1000); 527 (1000); 5
[17], Sierra LeoneThick blood film214 (8233)18 (6023); 3
[18], Sierra LeoneThick blood film214 (8233)23 (4230); 5
[20], EgyptThick blood film & ICT274 (1877)612 (1877)22 (1828); 5144 (1828); 5
[21], IndiaThick blood film678 (14963)4 (6649); 3
[19], NigeriaThick blood smear & ICT206 (4198)527 (2439)15 (1720); 7–10127 (1720); 7–10
[22], TanzaniaCounting chamber225 (919)68 (674); 3
[23], TanzaniaFinger-prick blood & ICT counting chamber & ICT210 (888)101 (953); 3
49 (855); 4
[24], TanzaniaCounting chamber & ICT225 (919)11 (393); 677 (393); 6
[25], TanzaniaCounting chamber & ICT225 (919)20 (60); 869 (422); 8
[26], IndonesiaThick blood smear & ICT193 (2165)47 (722)5 (1776); 310 (871); 3
[27], Papua New GuineaMembrane filtration & RACT106 (757)265 (558)7 (529); 393 (543); 3

Cases based on Mf antigen using the immunochromatographic test (ICT) or rapid-format antigen card test (RACT); Mf, microfilaria; N, sample size; MDAI, mass drug administration implementation; —: data not available.