Review Article

Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management

Table 1

Comparison of classifications of leprosy proposed by World Health Organization and Ridley–Jopling.

ClassificationBrief description

WHO (1987)Ridley–Jopling [21]Number of skin lesionsNeurological damageBacteriology: microscopic criteria
Paucibacillary
1 skin lesionTuberculoid (TT)Unique and infiltrated lesionsNo neurological damageNegative
2–5 skin lesionsBorderline tuberculoid (BT)Stasis and hypopigmented lesions few or many lesions of varying sizeLittle neurological damage little or no neurological damageNegative negative/1+
Multibacillary
>5 lesionsBorderline borderline (BB)Multiple lesions and maculopapularLate thickening of the nerve≧2+
Borderline lepromatous (BL)Multiple lesions, maculopapular, and nodulesLate thickening of the nerve≧2+
Lepromatous (LL)Multiple lesions, maculopapular, and nodulesLate thickening of the nerve≧2+

Note. 1+ or 2+: microscopic criteria when acid-fast bacilli were observed using Ziehl–Neelsen stain; negative, no acid-fast bacilli observed; BL, borderline lepromatous; BT, borderline tuberculoid; IND, indeterminate; LL, lepromatous leprosy; TT, tuberculoid leprosy.