Deglycosylation of Excretory-Secretory Antigens of the Second-Stage Larvae of Toxocara cati Improves Its Efficacy in the Diagnosis of Human Toxocariasis

Table 2

Sensitivity, specificity, positive predictive value, and negative predictive value of ELISA and western blotting using Toxocara excretory-secretory (TES) and deglycosylated Toxocara excretory-secretory (dTES) antigens for serodiagnosis of human toxocariasis.

Assay	ELISA using TES antigens	ELISA using dTES antigens	Western blotting using TES antigens	Western blotting using dTES antigens
Sensitivity (95% CI)	96.67% (82.78–99.92)	93.33% (77.93–99.18)	100% (88.43–100)	100% (88.43–100)
Specificity (95% CI)	80.00% (67.67–89.22)	88.33% (77.43–95.18)	95.00% (86.08–98.96)	98.33% (91.06–99.96)
PPV^1 (95% CI)	70.73% (59.19–80.1)	80.00 (66.45–88.98)	90.91% (76.85–96.79)	96.77% (81.12–99.52)
NPV^2 (95% CI)	97.96% (87.44–99.7)	96.36 (87.38–99.03)	100% (92.1–100)	100% (92.3–100)

¹Positive predictive value. ²Negative predictive value.