In Silico Study of Coumarins: Wedelolactone as a Potential Inhibitor of the Spike Protein of the SARS-CoV-2 Variants

Figure 1

Validation of the docking protocol. Comparative analysis of the binding interactions for the first docked molnupiravir (yellow) (a) versus the redocked molnupiravir (red) (b) in the binding sites of Omicron S-RBD. Superimposition of the two ligands, yellow and red (c) (RMSD = 0.9845 Å).

(a)

(b)

(c)