In Silico Study of Coumarins: Wedelolactone as a Potential Inhibitor of the Spike Protein of the SARS-CoV-2 Variants

Figure 10

BOILED Egg model of the selected compounds. The compounds lying in the white region of the egg are predicted to have a high probability of absorption through the human intestine, the compounds lying in the yellow (yolk) region of the egg are predicted to have a high probability of BBB permeation, and the compounds lying in the grey region outside the egg are predicted to have low HIA and limited BBB permeation [46]. Here, ceftazidime is out of range (TPSA = 244.76 Ų).